Organ transplants

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Organ transplants from living donors.

A. Survey of Transplantation Techniques The kidney is one of the few organs which can successfully be transplanted from a living donor with current techniques. Since a healthy donor can function satisfactorily with a single kidney, the removal of one of them for transplantation does not significantly endanger live.1,2,3 Removal, or substantial partial removal, of other organs, such a the heart,...

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Invasive pulmonary Aspergillosis in organ transplants--Focus on lung transplants.

Infections with filamentous fungi are common in transplant recipients. The risk for aspergillosis and other invasive pulmonary mycosis (IPM) is high in patients undergoing stem cell and lung transplantations. The mortality rates range from 20% to 60% and depend on a number of risk factors. The typical manifestations of IPM are lung infiltrates, consolidations, and fungal tracheobronchitis. The ...

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The use of cyclosporin in organ transplants

Cyclosporin is a metabolite isolated from culture broths of the fungus Tolypocladium inflatum Gams which was shown to be immunosuppressive by Borel et al. in rats, mice and guinea-pigs.1.2 Cyclosporin may directly block the release of interleukin I from activated T helper cells and indirectly block the release of interleukin II from macrophages, thus suppressing both cellular and humoral immuni...

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Organ Transplants from Living Donors – Halachic Aspects*

This manuscript is a survey of the halachic attitudes toward organ transplant procedures from a living donor which can be defined as life-saving procedures for the recipient or at least life-prolonging procedures. Three fundamental problems concerning the halachic aspects of such transplantation are discussed in detail: the danger to the donor, donation under coercion, and the sale of organs an...

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Organ transplants: the costs of success.

The current U.S. policy of "encouraged volunteerism" for the procurement of organs for transplantation is judged to be a failure. Demand is not being met, a complex and inefficient network of profit-making and not-for-profit procurement agencies has developed, and the opportunity for informed consent by relatives or friends in emergency situations is seen to be a "charade." Caplan advocates a...

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ژورنال

عنوان ژورنال: Nature

سال: 1996

ISSN: 0028-0836,1476-4687

DOI: 10.1038/379578c0